GLP-1 Weight Loss in Orlando, FL
FDA-approved GLP-1 therapy — medically supervised for real, lasting weight loss
GLP-1 receptor agonist therapy is the most clinically proven approach to medical weight loss available today. Our supervised program combines FDA-approved therapy with lab monitoring, nutritional coaching, and ongoing provider support.
Founder & CEO · Family Nurse Practitioner
FNP-BC since 2011 with 15+ years in ER, cardiology, neurology, and internal medicine. Passionate about medical weight loss, hormone replacement therapy, stem cell therapy, and peptide protocols — bringing the full power of regenerative and metabolic medicine to every patient.
Reviewed June 2026
COO · Family Nurse Practitioner
ER RN since 2009, FNP-BC since 2017. Passionate about HRT, joint injections, and skin health — including melasma and hyperpigmentation treatment. Brings clinical precision and cultural sensitivity to every aesthetic and wellness visit.
Reviewed June 2026
Every treatment at Rejuvenate & Wellness Center is designed, reviewed, and supervised by our board-certified providers — meet the team →
What Is a GLP-1 Receptor Agonist — and Why Is It Different?
A GLP-1 receptor agonist is a medication that mimics glucagon-like peptide-1, a natural hormone your gut releases after eating. GLP-1 signals your brain that you're full, slows the rate at which food leaves your stomach, and improves how your body handles blood sugar. In people with obesity, these signals are often blunted — GLP-1 therapy restores and amplifies them.
Originally developed for type 2 diabetes management, GLP-1 receptor agonists were found to produce remarkable weight loss in clinical trials. The landmark STEP 1 trial showed an average weight loss of 14.9% of body weight over 68 weeks in adults without diabetes. That's roughly 35 pounds for a 235-pound person. No prior FDA-approved weight loss medication had come close to these results.
At Rejuvenate & Wellness Center, we prescribe FDA-approved GLP-1 medications under the direct supervision of Marc Pierre-Louis, FNP-BC & Tamara Alicea-Nieves, FNP-BC. Our program is not a mail-order prescription service — it's a full clinical program with comprehensive lab work, dose titration, nutritional coaching, and regular provider check-ins to ensure you get the best possible results safely.
~15%
Average body weight lost in landmark clinical trial (68 weeks)
FDA
Approved for chronic weight management in adults with obesity
2x/mo
Minimum provider check-ins included in our supervised program
How Our GLP-1 Program Works
Step 1: Medical Evaluation & Labs
Before prescribing, our providers review your complete health history and order comprehensive bloodwork — metabolic panel, thyroid, HbA1c, lipids, and more. This ensures GLP-1 therapy is appropriate for you and establishes your baseline.
Step 2: Prescription & Dose Titration
We start at the lowest effective dose and titrate upward every 4 weeks based on your tolerance and response. This gradual approach minimizes side effects while building toward the full therapeutic dose.
Step 3: Nutritional Coaching
Our clinical team provides personalized nutritional guidance to complement the medication. We focus on sustainable eating patterns — not crash diets — that work with the appetite-suppressing effects of GLP-1 therapy.
Step 4: Ongoing Monitoring & Support
Regular check-ins with our clinical team, periodic lab rechecks, and protocol adjustments keep your program optimized. We track your progress, address any side effects, and celebrate your wins along the way.
GLP-1 vs. GLP-1/GIP Dual Receptor Agonist: Which Is Right for You?
Both medications are FDA-approved injectable receptor agonists and both are highly effective for weight loss. Here's how they compare — and how Rejuvenate Wellness Center decides which to recommend:
| Feature | GLP-1 Receptor Agonist | GLP-1/GIP Dual Receptor Agonist |
|---|---|---|
| Mechanism | GLP-1 receptor agonist | GLP-1 + GIP dual receptor agonist |
| Avg. weight loss | ~15% body weight | ~20–22% body weight |
| FDA approval | Approved for chronic weight management | Approved for chronic weight management |
| Dosing | Once weekly injection | Once weekly injection |
| Best for | Most patients; strong safety record | Patients needing greater weight loss or with insulin resistance |
Our providers evaluate your labs, health history, and goals to recommend the right medication for your specific situation.
Who Qualifies for GLP-1 Therapy?
FDA approval criteria for GLP-1 receptor agonist weight management therapy include adults with:
Unsure if you qualify? Book a consultation. Our providers will review your health history and determine whether GLP-1 therapy or another medical weight loss approach is appropriate for you — with no pressure to proceed.
Real Results from Orlando Patients
"The GLP-1 therapy completely changed my appetite. For the first time in years, I feel satisfied after a normal meal. I've lost 52 pounds and I'm still going."
Denise M.
Lost 52 lbs in 8 months
"The team at Rejuvenate Wellness Center was incredibly thorough. They found I had insulin resistance that was making weight loss nearly impossible. The program addressed everything."
Carlos V.
Lost 41 lbs in 6 months
"I was skeptical about injections but the team made it so easy. The side effects were minimal and the results have been life-changing."
Tanya B.
Lost 33 lbs in 5 months
GLP-1 Therapy FAQs
Common questions about GLP-1 weight loss in Orlando
Start Your GLP-1 Weight Loss Journey in Orlando
Book a consultation and find out if GLP-1 therapy is right for you.